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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

New Academic Head at South Campus to expand distance learning programmes into the global arena
2016-02-10

“Critical area of focus: Diversify provision, based on open learning principles, to improve learning opportunities across the post-school education and training sector” - SA Department of Higher Education and Training Strategic Plan 2015/16-2019/20

Open and distance learning (ODL) programmes will play a critical role in shaping the landscape of higher education. Not only does the South African Department of Higher Education and Training emphasise the importance of ODL, it is also contained within the United Nations’ Sustainable Development Goals. And now the University of the Free State (UFS) is becoming a major role player in the field through the cutting-edge ODL programmes offered by the South Campus.

Description: Jean Grundling  Tags: Jean Grundling

Jean Grundling has recently been appointed as the Academic Head of the South Campus.

At the helm of these programmes is the recently-appointed Academic Head of the South Campus: Jean Grundling. According to the new organisational structure of the South Campus, the Academic Head reports directly to the Campus Principal: Dr Daniella Coetzee.

“My role,” says Grundling, “focuses on developing and monitoring processes that will enable effective and efficient implementation of the three pillars of ODL.” These three pillars consist of:

• the design and development of quality learner-centred learning materials and tools during their ODL journeys;
• the selection, appointment, and development of competent facilitators to guide, coach, tutor, and support students; and
• the integration of administrative processes that will enable and support students to study at their own pace, place, and in their own time.

“Goal 4: Ensure inclusive and equitable quality education, and promote lifelong learning opportunities for all.”
United Nations Sustainable Development Goals

As part of her personal vision, Grundling would like to see the South Campus grow and develop into an institution that offers quality ODL programmes not only nationally, but globally. “I would like the South Campus to become an agent of social transformation in South Africa.”

Ultimately, Grundling’s wish is for the South Campus to contribute to the development and empowerment of people so that they can play a positive role in society.

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