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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS celebrates research excellence
2016-02-25

Description: UFS celebrates research excellence Tags: UFS celebrates research excellence

Researchers at the university were acknowledged for their new research ratings. From the left are: Prof Johann de Wet, Department of Communication Sciences; Prof Naomi Morgan, Department of Afrikaans and Dutch, German and French; Prof Corli Witthuhn, Vice-Rector: Research; Prof André Pelser, Department of Sociology; Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology; and Prof Riaz Seedat, Department Otorhinolaryngology.

During a recent gala occasion, the University of the Free State (UFS) acknowledged 15 of its researchers who received new ratings from the National Research Foundation (NRF).

According to Prof Corli Witthuhn, Vice-Rector: Research at the UFS, 37 applications have already been received for the next round of ratings by the NRF. In recent years, the university has experienced an increase in the rating of its researchers as the result of raised academic standards. These are in line with the Academic Project of the UFS. The UFS has 125 rated researchers in total.

The 15 recipients of new ratings from the NRF in 2015,are:

- Dr Tanya Beelders, Computer Science: Y2
- Dr Andrew Cohen, History: Y1
- Prof Pieter de Villiers, Theology: C2
- Prof Johann de Wet, Communication: C3
- Dr Angelinus Franke, Agriculture: C2
- Prof Jonathan Jansen, Education: B1
- Prof Riaan Luyt, Chemistry: B3
- Prof Naomi Morgan, Linguistics: C2
- Dr Trudi O’Neill, Microbiology: C1
- Prof André Pelser, Sociology: C3
- Dr Johann Rossouw, Philosophy: C2
- Prof Riaz Seedat, Health: C3
- Dr Jakub Urbaniak, Theology: Y2
- Dr Martin van Zyl, Mathematics: C3
- Prof Sue Walker, Soil, Crop and Climate Sciences: C1

The UFS also celebrated its five SARChI research chairs during this event. The main goal of the research chairs is to promote research excellence.

The five research chairs at the UFS are all established at Tier 1. Research chairs in the Tier 1 category are based on the researcher's research track record, as well as on the training record of his/her postgraduate and postdoctoral students.  Tier 1 research chairs are awarded to established researchers who are leaders in their field, and whose work is recognised internationally.

The following research chairs have been awarded to the UFS since 2013:

- Solid State Luminescent and Advanced Materials, Prof Hendrik Swart in the Department of Physics (2013-2017)
- Disease Resistance and Quality in Field Crops, Prof Maryke Labuschagne (2016-2020)
- Higher Education and Human Development, Prof Melanie Walker (2013-2017)
- Vector-Borne and Zoonotic Pathogens, Prof Felicity Burt (2016-2020)
- Humanities without Borders: Trauma, History and Memory (2016-2020) 

 

 

 

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