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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Shimlas shock Tuks by staying calm
2016-02-19

Description: KL News 2016 02 19 Varsitycup Tags: KL News 2016 02 19 Varsitycup
Prop Ox Nche was one of the substitutes who had a huge impact against Tuks in Pretoria on 15 February 2016. Nche and other Shimlas substitutes helped their team wipe out a massive deficit. Photo: Johan Roux.

He has never been involved in a match like this in his rugby career.
This is what Neil Claassen had to say about his team’s performance on 15 February 2016, when the Shimlas came up with one of the biggest fight-backs in the history of the Varsity Cup in Pretoria. According to the Shimlas Captain, his bench had a great impact, and this helped in shocking Tuks with 47-46 towards the end. This came after Tuks had been leading 43-15 in the 44th minute.

Great fighting spirit
The Shimlas' fighting spirit, and a new Varsity Cup points system in which converted tries may count up to 11 points, enabled them to wipe out this deficit.
“It was a tough match, especially after being so far behind,” Neil said.
“Coach (Hendro Scholtz) told us during half-time (when we were 15-36 behind) that we should stay calm."
“We weren't completely out of the game. We knew that if we eliminated unnecessary mistakes, we could make it.”

Impact from bench
This is the second consecutive match - the other was against Ikeys in Cape Town - where the Shimlas’ substitutes swayed the match. “The bench made a big difference,” Neil said. “We also scored an 11-point try, which helped a lot.”
The Shimlas’ fullback, Marco Mason, was named Player of the Match. He succeeded with a tricky conversion to gain victory for his team.

Injuries
The eighth man, Nardus Erasmus (knee) and flanker, Fiffy Rampeta (eye socket), sustained injuries, but should be able to play in the first home game against the Madibaz on 22 February 2016. The injured scrumhalf, Zee Mkhabela (concussion), could return for this match.
Shimlas are second on the log, with nine league points after two away matches. Maties has ten league points.

Young Guns get stuck
The University of the Free State (UFS') Young Guns got stuck 8-14 against Tuks in Pretoria on 15 February 2016.
Vishuis, the UFS's residence team, will start their onslaught in the residence league against Dagbreek in Stellenbosch on 22 February 2016.

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