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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Situation on the UFS Bloemfontein Campus under control after further disruptions
2016-02-23

State of our campuses #8

Further disruptions occurred on the Bloemfontein Campus of the UFS today after clashes between students on the campus last night. Members of the Public Order Policing had to disperse some students and the situation was stabilised in the early hours of the morning. No one was arrested and no major injuries occurred.

The clashes erupted last night after a group of protesters moved on to the field and disrupted a Varsity Cup rugby match that was already under way between the FNB Shimlas and the FNB Madibaz at Xerox Shimla Park. Subsequently the protesters were assaulted by some spectators who also ran on to the field.

Disruption continued this morning when students damaged some university property. Additional reinforcements from the South African Police Service were brought in to stabilise the campus. Some outsourced contract workers and students are still demonstrating outside the Main Gate of the campus on Nelson Mandela Avenue. The campus is relatively calm now and matters are under control.
The safety of students in residences on campus is the major concern for the senior leadership of the university and extra care is being taken to ensure their safety. In one case a residence had to be vacated and alternative accommodation was arranged for the students. The situation is under control in other residences. 

The Bloemfontein and South Campuses are closed from 23 to 24 February 2016 and no academic and administrative services are available.

Members of the university’s Protection Services and the South African Police Service are on the Bloemfontein Campus and are monitoring the situation closely.

A comprehensive investigation about the course of events that took place on the Bloemfontein Campus since yesterday morning continues.

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