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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Regional winner designing her way to Architectural Student of the Year Award
2016-03-09
Musa Shangase, Corobrik Commercial and Marketing Director, and Nilene van Niekerk. |
For 29 years, Corobrik has been celebrating the most outstanding architectural talent in South Africa. This year, Nilene van Niekerk – a master’s graduate of the University of the Free State (UFS) Department of Architecture – features as one of the regional winners.
Deciding on a dissertation topic, Nilene contemplated how she could use architecture as a tool to address a non-architectural contemporary problem specific to post-apartheid democratic South Africa. Her answer was born from her passion for freedom of speech. “Freedom of speech and the intimidation of journalists by the controversial Secrecy Bill were at the forefront these past few years,” Nilene says. “Although freedom of expression are generally protected practices in South Africa’s constitution, the persistent role of the government to protect state information is a substantial threat to citizens’ constitutional right of freedom of expression.”
This resulted in Nilene’s dissertation topic, Freedom of Expression Forum. This architectural concept envision a building, in the vicinity of Constitutional Hill, that symbolises protest against the Secrecy Bill. The building will provide “protection to journalists and become a pivotal point where classified information can be sent and archived. It will also establish a public space that encourages communication – all in the name of fostering the right of freedom of expression within this human rights precinct,” Nilene says.
Nilene will now go on to compete for the national title at the Corobrik Student Architect of the Year Awards in Johannesburg in May 2016.
“The project also rethinks the idea of sustainability as it focuses on how to contribute to a sustainable political future in South Africa. I believe that we as architects, especially in a third world country, should think beyond the normative boundaries of sustainability,” Nilene says.