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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Leading African Studies scholar to represent UFS as research fellow at Leiden University
2016-03-10

Description: Dr Stephanie Cawood Tags: Dr Stephanie Cawood

Dr Stephanie Cawood to devote three months at the African Studies Centre Leiden as a visiting research fellow to further her research on the rhetorical imprint of Nelson Mandela.
Photo: Supplied

Dr Stephanie Cawood, Programme Director and Senior Lecturer at the University of the Free State (UFS) Centre for Africa Studies has been offered a visiting research fellowship to the African Studies Centre Leiden (ASCL) at Leiden University in the Netherlands. The ASCL is entirely devoted to the study of Africa transcending multiple faculties and is known for its extensive library.

As a visiting research fellow from April to June 2016, Dr Cawood looks forward to expanding her network as well as intellectual horizons with the broad spectrum of knowledge archived by the ASCL. “Working so closely with the scholars at the African Studies Centre Leiden will enrich my research and broaden my international footprint as a scholar,” Dr Cawood says.

Her research at ASCL follows on her doctoral research on the former president of South Africa, Nelson Mandela’s rhetorical imprint, and will explore the conceptual, cultural, ideological and historical influences that shaped the thought and rhetoric of Nelson Mandela. She is particularly interested in studying the intertextual dynamics in Mandela’s rhetoric with historical figures such as Jawarharlal Nehru, Martin Luther King Jr and Winston Churchill.

According to Dr Cawood, this research “will deepen the understanding of Nelson Mandela’s rhetorical journey from struggle to liberation and unpack the various influences that made him the political figure he ultimately became.”

During her tenure at Leiden University, Dr Cawood will prepare a manuscript to be published by the ASCL as a working paper and also present seminars.

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