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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Arment-My-Nie proved what a time it is to be alive at the 2016 Stagedoor
2016-03-15

Description: 2016 03 KL Stagedoor Tags: Stagedoor

2016 has been nothing short of events that have left students singing the phrase, “What A Time To Be Alive!” This year’s Stagedoor theme had first-year groups re-enacting some of the most memorable times of 2016 and even far into the future.

On 12 March 2016, the show continued with the newly adopted format which was initiated last year, whereby residences are coupled together. With all teams being entered into the finals round, this can be seen as a victory for all, as the crowds of students and parents had the opportunity to see all pairs perform.

Kovsie Church, on the Bloemfontein Campus of the University of the Free State, was packed wall-to-wall with fans and supporters who were high in anticipation of the never-seen-before performances. This resulted in even more excitement for audiences and a tight competition for the residences.

With the theme already set out, the show began to roll, and audiences were enticed with each performance. Audiences experienced the tongue-in-cheek wit of performers, as many scripts had underlying references which left viewers roaring with laughter.

Only three groups could, however, walk away with the top spots. Karee and Arista were third, with Sonnedou and Villa Bravado coming out second, and the trophy was taken by Armentum and Vergeet-My-Nie.

This year, the Arts and Culture office of the Student Representative Council introduced additional categories to the competition. The winners were:

  • McDonalds Jingle – Legatum and NJ van der Merwe

  • Best Actor – Bernie Neser

  • Best Actress – Maynie Knoetze

  • Best Incorporated Theme – Legatum and NJ van der Merwe

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