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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

School of Medicine White Coat ceremony embraces first-years into the fold
2016-03-17

Description: School of Medicine White Coat ceremony  Tags: School of Medicine White Coat ceremony

From the left are first-year UFS medical students Liandri Van Zyl, Lane Halberg, Wisani Baloyi, and Neve Steenbeek at the annual White Coat ceremony, wearing their white coats for the first time.

“Life isn’t about yourself. It’s about what you can pour into the lives of others.” The first-year medical students will not soon forget Dr Lynette van der Merwe’s words during their recent White Coat ceremony. Dr Van der Merwe is the Programme Director of the MBChB undergraduate program at the University of the Free State (UFS) School of Medicine.

The annual White Coat ceremony is a tradition at the school to welcome first-year students to the world of medicine. As an official initiation into this new world, students are allowed to put on their white coats for the first time. During the ceremony, representatives from the Medical Students Association contributed to the significance of the event by reading a declaration of intent regarding professional behaviour for all medical students.

Dr Wayne Marais, Head of the UFS Department of Ophthalmology, was the guest speaker, sharing his vivid memories of being the first black student to study Medicine at the UFS in 1987. Prof Marais encouraged students to embrace their failures and successes, and to ultimately stay true to themselves – both personally and professionally.

Second-year medical students were at hand to offer advice and support. In addition to offering encouragement, they also assured the newcomers that there is a life outside of their books as well.

The entire ceremony not only served to welcome the first-years into the fold, but also unite them in a common purpose towards helping others in future.

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