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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Medical students enrich lives through community service project
2016-03-18

Description: 2016 03 18 Outreach  Tags: 2016 03 18 Outreach

A group of third-year medical students organised a fun day for Ons Kinderhuis as part of their community service project.

As part of their curriculum, third-year MBChB students are required to complete a community service project in collaboration with a specific NGO in Bloemfontein. Not only do these projects serve an academic requirement, but also echo the spirit of service and compassion emblematic of the Human Project of the University of the Free State (UFS).

 

One group of students chose to pour their time and care into Ons Kinderhuis–home to 100 children with special needs. Since their involvement, these medical students have helped improve the home’s facilities and also hosted various fun days for the staff and children.

 

The latest fun day was celebrated on Saturday 12 March 2016. The festivities were kicked off in the morning by a game of soccer using the brand-new goal posts recently built by the medical students. It was difficult to decide who were more excited – the children or the staff – when some of the Cheetah rugby players joined the event. A slippery slide came in handy to wash off sticky hands and mouths and for little bodies with lots of energy the jumping castle was a perfect answer. Faces were painted and a banner created while music and the smell of the braai floated into the autumn air.

 

“I couldn't help but be proud of my team and thankful for this opportunity,” said Willem Potgieter, one of the student volunteers. Seeing the smiles on the children’s faces made it all worthwhile. “It was truly a humbling and a great learning experience for each and every one of us,” Willem said.

 

This group of medical students consist of Burger Oosthuizen, Marié Engelbrecht, Lourens Badenhorst, Dirki Wessels, Roodt Ehlers, Shirley-Louise du Plessis, Mariet Geldenhuys, Louise-Mari Zietsman and Willem Potgieter.

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