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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Five Kovsies competing at National Championship for Physically Disabled
2016-03-18

Description: CUADS Tags: CUADS

Students from the University of the Free State (UFS) will compete at the Nedbank National Championship for the Physically Disabled in Bloemfontein from 21–23 March 2016. From back left is Johann van Heerden, Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, and Danie Breitenbach. Front from left is Louzanne Coetzee and Dineo Mokhosoa.
Photo: Jóhann Thormählen

Five students from the University of the Free State (UFS) will be taking part in the Nedbank National Championship for the Physically Disabled from 21–23 March 2016 in Bloemfontein. Dineo Mokhosoa, Juanré Jenkinson, Louzanne Coetzee, Danie Breitenbach and Johann van Heerden will represent the Free State at this event – one of the last opportunities to qualify for the Paralympic Games.

According to Martie Miranda, Head of the Center for Universal Access and Disability Support (CUADS) at the UFS, these students have shown they can achieve anything. “The Center for Universal Access and Disability Support is extremely proud of our students with disabilities who excel in sport and wish our students the best of luck with the national championships,” she said.“They confirm that ‘impossible’ is just a word.”

Most of the students already have excellent national and international rankings in their respective categories.

Mokhosoa (Cerebral Palsy), is ranked first in South Africa in discus, shot-put and long jump. This Social Work student also has two South African records in shot-put and long jump respectively behind her name. Jenkinson (Cerebral Palsy) is ranked eighth in the world in shot-put.

Coetzee (blind), who competes in the 800 m, 1 500 m and 5 000 m, is fifth in the world in the 800 m and ninth in the 1500 m. Breitenbach (blind) runs 400 m, 800 m and 1 500 m. Breitenbach, a Law student, is ranked fifth in the world in the 800 m.

Van Heerden (Cerebral Palsy) competes in swimming in the 50 m, 100 m and 200 m breaststroke. The Education student is ranked third in the 50 m, seventh in the 100 m and third in the 200 m in the world.

The Paralympic Games is taking place in September 2016 in Rio de Janeiro, Brazil.

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