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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
UFS Ground Studies Laboratory receives accreditation to international standard
2016-03-18
Lore-Mari Deysel, Deputy-Director of the institute for Groundwater Studies.
Photo: Charl Devenish |
The Institute for Groundwater Studies (IGS) Laboratory at the University of the Free State is on equal footing with international testing labs. With its accreditation in March 2016 by SANAS (South African National Accreditation System), the IGS Laboratory now officially meets global standards.
Quality of water
The IGS Laboratory mainly analyses the quality of water samples. When it was originally established in 1989, the lab’s central function was to conduct testing for researchers at the institute itself. “After the public and water boards realised their need to analyse water samples, the IGS Laboratory expanded to deliver a service to these clients,” says Lore-Mari Deysel, Deputy-Director of the institute.
Since suppliers and regulatory authorities will not accept test or calibration results from a lab that is not accredited, the IGS initiated the accreditation process.
Accreditation to international standard
In order to be deemed technically competent and able to receive accreditation, labs must meet the ISO/IEC 17025 standard. ISO/IEC 17025 was first issued in 1999 by the ISO (International Organization for Standardization) and the IEC (International Electrotechnical Commission).According to Deysel, this is the single most important standard for calibration and testing laboratories around the world.
“Laboratories that are accredited to this international standard have demonstrated that they are technically competent and able to produce precise and accurate test and/or calibration data. Furthermore, it demonstrates that the university has the capacity to supply valuable and reliable services alongside the academy,” Deysel says.