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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Osaka University in Japan joins forces with UFS to discuss SA and Africa
2016-03-23

Description: Yani Karavasilev  Tags: Yani Karavasilev

Yani Karavasilev of Osaka University speaking about political stability and Foreign Direct Investment in the Southern African Development Community on day-2 of the joint conference between Osaka University and the University of the Free State.
Photo: Dr Marina da Silva

Recently, international delegates convened for the annual Osaka University-University of the Free State (UFS) Conference to discuss issues that affect Africa. This high-profile conference was hosted by the UFS Department of Political Studies and Governance from 22-23 February 2016. The event focused its attention on the state of South Africa (SA) as well as conflict resolution on the African continent.

Topics of discussion

Scholars and policymakers proceed to map out the political, economic, social, and educational trajectory of SA and the African continent. Some of the topics of discussion included SA politics, democracy, economy, foreign policy, race, education, and peace. Delegates also looked at foreign direct investment in the Southern African development community and organisations such as the United Nations and the African Union.

Entangled in turmoil

At the conference, Prof Virgil Hawkins of the Osaka School of International Public Policy, (Osaka University) presented a paper entitled: The role of the local media in Burundi’s 2015 coup attempt. In his presentation, Prof Hawkins analysed the impact made by Radio Publique Africaine, Renaissance, Isanganiro, and Bonesharadio stations during the conflict. Had it not been for these private radio stations, the events leading to, during, and after the coup would not have received international coverage.

Prof Hawkins explained that prior to the coup, “key private radio representatives were called to Musaka military camp” by former intelligence chief, Major General Godefroid Niyombare. He informed them about the coup plot and urged them to report on it. The government in turn accused the independent media of colluding with the coup conspirators. As a result, the radio stations were attacked, coerced to go off-air, and subsequently destroyed. Despite overt efforts by the state to suppress the media’s freedom of expression, it did not succeed.

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