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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Book Prize for Distinguished Scholarship awarded to Dr Christian Williams
2016-03-24

Description: Dr Christian Williams Tags: Dr Christian Williams

Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State and Dr Christian Williams, senior lecturer at the UFS Department of Anthropology.
Photo: Johan Roux

When Dr Christian Williams moved from the United States to Namibia in January 2000 as part of the WorldTeach volunteer programme for teachers, he had not anticipated an award-winning piece of scholarship in his future. It was during these visits to Namibia, though, that the seeds for his highly-acclaimed book were sewn.

While volunteering at the St. Therese Secondary School in Tses at that time, Dr Williams – now a senior lecturer at the University of the Free State (UFS) Department of Anthropology – became acquainted with some of the school’s alumni. The stories these individuals started sharing with him soon revealed personal histories of exile and violence by fellow SWAPO (South West Africa People’s Organization) members.

These experiences ultimately resulted in Dr Williams’ book, National liberation in postcolonial southern Africa: a historical ethnography of SWAPO’s exile camps, published last year. Due to the book’s literary impact, the university awarded Dr Williams the UFS Book Prize for Distinguished Scholarship on Friday 19 February 2016. Dr Williams is the second academic to be awarded this prize.

Politics of the past


In the 1960s, Namibians mobilised and retaliated against colonial rule under the liberation movement known as SWAPO. This created political tension which resulted in the flight of many SWAPO members to exile camps administered by the party.

“Over its three decades in exile, SWAPO was responsible for the welfare of roughly 60 000 Namibians. This was about 4% of the total Namibian population at independence – most of whom lived in camps,” says Dr Williams. The research originally used as a basis for his doctoral thesis was subsequently developed into this prize-winning book.

Advancing the Human Project

“It’s an honour to receive recognition from the university; it means that they value the kind of work that I am doing. I think it’s great for universities to have such prizes,” Dr Williams says.

Supporting the UFS Human Project, Dr Williams will donate a portion of the R25 000 prize money towards the UFS Student Bursary Fund Campaign, as well as the school in Namibia.The rest will subsidise the purchase of the book for distribution to libraries and as gifts.

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