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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Pauline Gutter’s metaphorical representations of South Africa
2016-04-07

Description: Thamsanqa Malgas  Tags: Thamsanqa Malgas

Art student, Thamsanqa Malgas views the Purgatorium exhibition at the Stegmann Gallery on the Bloemfontein Campus (UFS).
Photo: Rethabile Isaacs

Purgatory is a temporary condition of torment or suffering. This is the central thread of the renowned artist’s exhibition, Purgatorium, at the University of the Free State (UFS). Pauline Gutter’s exhibition was opened by Harry Siertsema on 9 March 2016 at the Stegmann Gallery on the Bloemfontein Campus.

The artist, who grew up on a farm in the Free State, is influenced by animals and farm life. “My work is on many levels a metaphorical representation of the violence of current South Africa. Some people want to move away from stigma, others adopt hysteria. The impressive yet vulnerable bulk of the bulls depicted in uncomfortable positions manifests the voiceless and powerless generation of food producers in their daily struggles for survival,” she wrote in the catalogue of the exhibition.

Prof Dirk van den Berg of the UFS Department of History of Art and Image Studies wrote an essay about the exhibition, in which he captures the lived endurance of stress and suffering which Pauline Gutter depicts vividly in Purgatorium.

“The paintings, drawings, and prints in this exhibition have, in various ways, the effect of disseminating the basic tenor of the weaning metaphor of struggle for survival into the farming domains of the land, its creatures, and its people,” said Prof van den Berg.

Art student, Thamsanqa Malgas, was very impressed with the exhibition, saying that it was a fascinating collection, and a must-see for art lovers. The exhibition closed on 1 April 2016.

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