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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Vishuis’s fourth Varsity Cup victory about more than rugby
2016-04-15

Description: Vishuis Tags: Vishuis

House Abraham Fischer, a residence from the University of the Free State, is the most successful team in the history of the Varsity Cup. Vishuis beat Patria (Pukke) in the 2016 final of the tournament.
Photo: SASPA
 

For Vishuis, it is about more than just rugby.

This is what Henco Posthumus, captain of House Abraham Fischer’s rugby team, had to say after his team was crowned the national Varsity Cup champions for an incredible fourth time. According to the flyhalf, the title of the leading residence team in the country is “special for the guys”.

Vishuis is the most successful residence team in the history of the tournament. Apart from their four titles, they have played in a total of five Varsity Cup finals.

On 11 April 2016, the residence from the University of the Free State (UFS) launched a great comeback in Stellenbosch to beat Patria (Pukke) by 37-29. This victory ensured that Vishuis was unbeaten in 2016.

Great fighting spirit


The Kovsies started off well against Patria, but were behind 16-29 shortly after break, and had to “delve deep”, according to Posthumus. “To be behind in this way is not what one would prefer. For some reason, we have been in similar situations before, and we know how to make a comeback,” he said.

“We looked one another in the eye and decided that we are not going to lose again in the final.” In last year’s final in Bloemfontein, when Posthumus played at fullback, Vishuis got stuck against Mopanie (Tuks) at the end of the match, and they wanted to prevent this from happening again.

Heymans a hero


According to the Vishuis captain, one of his team’s assistant coaches, Franco (Vaatjie) van der Merwe, spoke harshly to the players when they were behind. The victory was clinched in the dying moments, with the second try of scrumhalf, Ruben Heymans, when the score was 29 points each. Heymans was a star, and the well-deserved Man of the Match.

Posthumus said it is a great privilege to carry the title of Varsity Cup champions. His team has worked hard to reach the top.

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