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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS to establish Sesotho language research and
2004-12-01

The Council of the University of the Free State (UFS) approved the establishment of a Sesotho Language Research and Development Centre.

The centre will be established on request of the national Department of Arts and Culture and will be situated at the UFS’s Vista campus.

According to the Dean: Faculty of Humanities at the UFS, Prof Gerhardt de Klerk, the national department has committed itself to make available R1-million for the project. An amount not exceeding 3,5 percent will be paid to the UFS in payment of costs incurred in terms of the housing of the centre.

“The tasks of the centre will include the promotion of indigenous languages and terminology development; the research, development and maintenance of a terminological data base and the writing and publishing of various genres of literature in co-operation with relevant and interested parties,” says Prof de Klerk.

Other tasks include the establishment and maintenance of a language museum, outreach to the community and the mobilisation of support for the use of African languages.

“The centre will be managed by a management committee consisting of a representative of the Department of Arts and Culture, the academic registrar, head of the Department of African Languages, chief financial official of the UFS, a member of the UFS Senate, a senior lecturer/professor from the School of Languages/ Faculty of the Humanities, the head of the provincial language unit and a representative of PANSAD,” says Prof de Klerk.

Media release
Issued by: Lacea Loader
Media Representative
Tel: (051) 401-2584
Cell: 083 645 2454
E-mail: loaderl.stg@mail.uovs.ac.za
1 December 2004

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