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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

“A night of celebration” – Dr Van der Merwe
2016-05-04

Description: “A night of celebration” – Dr Van der Merwe Tags: “A night of celebration” – Dr Van der Merwe

The University of the Free State Faculty of Health Sciences held its annual prize function on 11 April, to celebrate the achievements of its top students from the three schools within the Faculty. Dr Lynette van der Merwe, undergraduate programme director at the School of Medicine, described the night as a celebration of success on many fronts.

The School of Medicine, Nursing, and Allied Health Professions gave students various awards, medals, and trophies for their academic performance and achievements in 2015.

Students encouraged to seize the day

Professor William Rae, Head of Medical Physics at the School of Medicine, was the occasion’s guest speaker. He encouraged students to use the limited time each one of them has in the world to the best of their abilities by always seizing the day. “As prize winners, be leaders, changers in the world. Seek more, appreciate diversity, and mingle with people different from you; always overflowing with joy,” concluded Prof Rae.

Best overall students


Belinda Meyer received the award for best final-year student in the School of Allied Health Professions. Hailing from Potchefstroom, Meyer obtained her Bachelor in Occupational Therapy degree with distinction, and was nominated as the top achiever of her year.

In the School of Medicine’s undergraduate medical programme, Pieter Jan Louw was recognised as the final-year student with the highest academic achievement in all study years. He went on to receive his degree cum laude.

Michelle Horvath, a BSocSc Nursing student, received an award for being the student who displayed the most professional growth during her training. Her years of study were described as being characterised by perseverance and a sense of duty and professionalism.

And lastly, the trophy for the student with the best results in a first Bachelor’s degree in the Faculty was awarded to Karl Nicholas Sachse, who completed his degree in BMedSc (Radiation Sciences) cum laude. Recognised as one of the top five students in his first, second, and third years of study, Sachse is currently doing his BMedSc Honours in Medical Physics.

The evening carried with it its own special ambiance as achievements were celebrated by students, their families, and staff members from the Faculty.

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