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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

We must rise again, says Dr Luescher
2016-05-04

Description: 2016 05 04 Dr Luescher sml Tags: 2016 05 04 Dr Luescher
Dr Thierry Luescher, Assistant Director of University of the Free State Directorate for Institutional Research and Academic Planning, was one of the guest speakers at the first TEDxUFS event of the year on the Bloemfontein Campus. Here he is explaining where the #movements started, and how to change the way we think. Photo: Marli du Plessis.

The student protests, known as the #MustFall movements, started on 9 March 2015, when students protested in a well-rehearsed manner at the Cecil John Rhodesstatue at the University of Cape Town. After this protest, students all over South Africa started their own movements from #OpenStellies to #SwartsMustFall, the latter happening on the Bloemfontein Campus of the University of the Free State (UFS) in March 2016. But, as Dr Thierry Luescher, Assistant Director of UFS Directorate for Institutional Research and Academic Planning, says: “We shall soon run out of #MustFalls. Maybe it is time that we rise again.”

The first TEDxUFS was held on Friday 15 April 2016 at the New Education Building on the Bloemfontein Campus of the UFS. Dr Luescher shone light on the way we look at hashtag movements. At the conference, he was one of the guest speakers who shared their perspectives on the theme of #ImpossibleIsNothing. The others were Ndumiso Hadebe, and Fezile Sonkwane.

Changing angles

No matter what the issue, whether it is on a campus or not, the same reaction can be expected by all: they burn things to get attention. In retrospect, this is our political culture. This is what we have been told to do if we need answers. There is a much faster and cheaper way to attract people’s attention: the hashtag movements, says Dr Luescher.

Stop the fire

He argues that we should stop burning down buildings and vandalising properties. What we need is people with intellect to use their words. We, as students, have to take back our voice. We need to stop this self-pitying, and take a stand.

Students have the power to change lives. We would be able to reach as many as 1.4 million people with our tweets or instagram accounts. According to Dr Luescher, the time for violence has come to an end.

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