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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Cream of the crop of Grade 12 learners invited to become part of Kovsie family
2016-05-06

Description: 2016 Top achievers Tags: 2016 Top achievers

“You are all here because we believe in you, the cream of the crop of Grade 12 learners in Bloemfontein. We acknowledge you, and hope that you will entrust us with your future, and become part of the Kovsie family.” With these words, Nomonde Mbadi, Director of Marketing at the University of the Free State (UFS), welcomed selected guests to a function dedicated to the top achievers at their respective secondary schools.

Prof Jonathan Jansen, Vice-Chancellor and Rector of the UFS, highlighted an aspect of the university that is often overlooked.  “It is extremely important that you not only achieve a degree at university … The greater goal of education is to provide a set of values with which you can interact with humankind.”

Showcasing some of the university’s most talented students, Prof Jansen highlighted achievers such as Nozimanga    Bonje, who overcame tragedy, trauma, and hardship to attain her BSc in Genetics and is now studying for her Honours degree; and Tanya Calitz, a newly-graduated (summa cum laude) law student now clerking for Deputy Chief Justice, Dikgang Moseneke, in the Constitutional Court. Prof Jansen also conducted an interview with Kovsies’ sport star, Wayde van Niekerk, who won gold last year in the 400m at the IAAF World Championships in Beijing.

Learners were given the opportunity to pose questions to Prof Jansen, and, afterwards, to interact with deans and faculty marketers to obtain relevant information. The Admissions Department also had several workstations set up with staff members on hand to facilitate online applications for those who had already chosen a field of study.

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