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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Van den Oever gives students a different perspective
2016-05-06

Description: Prof Van den Oever gives students a different perspective Tags: Prof Van den Oever gives students a different perspective

Prof Annie van den Oever from the Netherlands presented a series of guest lectures on media technologies to students of the Film and Visual Media Programme at the University of the Free State (UFS). Here from left is Chris Vorster, lecturer in Drama and Theatre Arts, Prof Van den Oever, and Dr Pieter Venter, Senior lecturer at Drama and Theatre Arts.
Photo: Jóhann Thormählen

She played a part in conceptualising the Film and Visual Media Programme at the University of the Free State (UFS), and sees film from a perspective different from most young South Africans.

According to Chris Vorster, lecturer of the UFS BA Honours degree in Film and Visual Media, this is one of the reasons why Prof Annie van den Oever’s visit is of such great value. The actor, who is a lecturer in Drama and Theatre Arts, believes it is important to expose his students to influences outside their normal experience.

Prof Van den Oever, an extraordinary professor at the UFS since 2011, presented a series of guest lectures on media technologies from 11-14 April 2016 at the Audio Visual Studio on the Bloemfontein Campus. She is a senior researcher for Film at the University of Groningen in the Netherlands, and an Associated Researcher for Film at Paris 1, Panthéon Sorbonne, in France.

Another milieu

“It is invaluable for students, in any field of study, to receive as many influences from the outside. Therefore, it is important to have someone here from another milieu and context. And academically, she is outstanding,” says Vorster.

Vorster’s students are also exposed to practical expertise from the industry in the country, not only academics.

Relationship with UFS

Prof Van den Oever says she usually visits the UFS twice a year. Her recent lecture series on media technologies was about the power of visual and film culture today, and how you can understand its powers. “Why strange effects work strongly and why the strange is inserted, because people respond strongly to them,” she says.

Prof van den Oever enjoys meeting new people, and often works with colleagues from the UFS on various projects. She also is full of praise for the management of the university. “It is great to work across cultures, and be part of a university in transition.”

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