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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Expansion to Physics building officially opened on Bloemfontein Campus
2016-05-06

Description: New Physics building  Tags: New Physics building

The newly-opened addition to the Physics Building on the Bloemfontein Campus.
Photo: Charl Devenish

An extension to the Department of Physics at the University of the Free State (UFS) was officially opened on the Bloemfontein Campus on 20 April 2016.

“This started off about five years ago when we were talking about not having enough room for large classes. Prof Matie Hoffman suggested that we build a large lecture room on our parking space,” said Prof Hendrik Swart, Professor in the Department of Physics as he addressed guests at the official opening ceremony.

“A year later, we received a Sarchi Research Chair [South African Research Chairs Initiative] on Advanced and Luminescent Materials. We needed more office and laboratory space. The two ideas were combined and presented to the university’s senior management,” he added.

When the university was founded in 1904, Prof James Lyle was appointed to head up the Physics and Chemistry departments. Five years later, a single room was allocated for the Physics laboratory in the main building upon its completion. In 1947, the old Physics building was designed and constructed. Fast forward 69 years, the department has reached another milestone. Facilities accommodated by the expansion include a new telescope for astrophysics experiments, a basement for storing old equipment, as well as a sliding trap door which allows heavy goods to be elevated into the building from the ground floor. The telescope is one of the many unique features of the building given its capacity to expose graduate students to the basic techniques of radio astronomy, especially in light of the fact that the SKA (Square Kilometre Array) project which is in progress.

“Our department is extremely strong at this stage, and a bright future lies ahead,” said Prof Koos Terblans, the Head of Department. The opening also served to celebrate the 103 publications achieved by the department last year.

Dr Lis Lange, Vice-Rector: Academic is proud of the heights reached by the department to date. “The Department of Physics is undoubtedly one of the jewels in the crown of our university, and we are very proud of its developments. Universities are built on legacies, and they are also about change, which is what this department has been demonstrating.”

The expansions to the building with its top-class facilities, was constructed at a cost of R25 million – an infrastructure grant courtesy of the Department of Higher Education and Training.

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