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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Former UFS Dean awarded SAAWK medal for contribution to Bible translation work
2016-05-09

Description: Prof Hermie van Zyl Tags: Prof Hermie van Zyl

Prof Hermie van Zyl
Photo: Eugene Seegers

Prof Hermie van Zyl, former Dean of the Faculty of Theology at the University of the Free State (UFS), was recently awarded the Ds Pieter van Drimmelen medal by the South African Academy of Science and Arts (SAAWK) for his contribution to Afrikaans Bible translation and other translation work.

Prof Van Zyl was part of the team that published the Interlinear translation of the Bible (New Testament) in Greek and Afrikaans. This translation takes the reader from the original text (Greek), to an almost verbatim version, to a rough translation, and, ultimately, to a more polished, finished translation in the target language of Afrikaans.

Other translations Prof Van Zyl has been involved in include the Afrikaans Bible for the Deaf (published in 2008), the direct translation of the Bible (of which the New Testament and the Psalms have already been published), the New Living Translation, the Parallel New Testament, and the Reference Bible. He is the first lecturer from the Faculty of Theology at the UFS to receive an award from the SAAWK.

“It is a wonderful privilege and an honour and really came out of nowhere,” said Prof Van Zyl. He added that he is grateful that, amongst all the wonderfully talented people at the UFS, he could make a modest contribution. He mentioned that the collegial conversations, seminars, and other discussions in the faculty over the years, were very stimulating. He singled out Prof Jan du Rand and Prof Francois Tolmie (another former Dean of the Faculty and long-time colleague in the department of New Testament Studies) as inspiration.

The official presentation of the medal will take place in the Atterbury Theatre in Pretoria on 29 June 2016.

Prof Van Zyl was employed in the Faculty of Theology at the UFS for 29 years until his retirement in 2013. He is currently a Research Fellow in the Department of New Testament, and still lectures on occasion.

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