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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Internationally-renowned futurist proposes innovation in corporate management
2016-05-10

Description: Pieter Geldenhuys  Tags: Pieter Geldenhuys

Pieter Geldenhuys, guest speaker at the seminar, who mapped the future of corporate management  (left) with Dr Vic Coetzee, Senior Director: Information and Communication Technology Services at the UFS (right).
Photo: Hatsu Mphatsoe

Humans need to adapt their thinking to the world’s changes. This is Pieter Geldenhuys’s conviction.

The Information and Communication Technology Services (ICT) at the University of the Free State hosted a seminar on 22 April 2016 at the Bloemfontein Campus. Geldenhuys, the Director of the Institute for Technology Strategy and Innovation at North-West University and internationally-renowned futurist, presented his views on technology, innovation, and corporate management on this occasion.

Geldenhuys, a well- known speaker, academic, and futurist, is in the business of identifying opportunities in the changing technological and social landscape with the aim of assisting companies to prepare for the future, while being an active agent in defining it. Lately, he has been exploring the concept of a new kind of management science, which he believes is a prerequisite for institutions such as ours.

This management science incorporates physics in improving corporate management. “We have an unbelievable grasp of the world of physics,” he said, suggesting that we use our knowledge of nature to capitalise on individual and collective strengths within institutions.

He said that minor changes can change one’s future or that of an organisation completely. He even went as far as to state that the culture of an organisation is the one that determines how well you do. Relating to the adaption of organisations in a constantly changing and dynamic environment, Geldenhuys advised that, “when faced with disruption, don’t retaliate; accept.” 

By making use of different tools, such as technology aw well as social and business trends, Geldenhuys is adamant that corporations and institutions will adapt easily to the world’s complex systems.

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