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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Johann swims his way to Olympics
2016-05-18


Johann van Heerden from the University of the Free State has qualified for the Paralympic Games in the swimming pool, and is now waiting to hear if he will be included in the South African team. Photo: Nadya van Heerden.

In the past couple of months, Johann van Heerden has been swimming his way to the Paralympic Games, and is still preparing as if he will be going to Rio de Janeiro.

The Kovsie swimmer, who will know whether he has been included in the Paralympic team in July 2016, feels his training is progressing well. The Olympics will be held in Brazil from 7 to 18 September 2016. If all goes well, this could be the first of several Olympics for the 20-year-old second-year Education student from the University of the Free State (UFS).

Dream year for Education student

Van Heerden (cerebral palsy), whose hero is the former Paralympic superstar Natalie du Toit, has had huge successes in the run-up to the 2016 Olympics. Among others, he was named the best senior swimmer at the Nedbank National Championships for the Physically Disabled in Bloemfontein in March 2016. At the South African Senior Championships in Durban in April 2016, he qualified for the Olympics in the 100 m breast-stroke with an A-qualifying time, and in the 50 m and 100 m freestyle with B-qualifying times.

Only three male swimmers to Olympics

However, he has to wait until the announcement of the South African Paralympic team, since only three male and three female swimmers will be selected. He will not be competing in another major event before the Olympics. “My short-term goal is to compete in this year’s Games, and, in the long term, I would like to reach even greater heights at the 2020 Games,” he said. Du Toit is an inspiration to him because “she was hard-working, and she had a lot of drive”.

Other students from CUADS also excel

At the above-mentioned National Championships, Van Heerden won a total of five gold medals (200 m medley, 100 m breaststroke, 50 m freestyle, 50 m breaststroke, and 200 m breaststroke) and one silver medal (100 m freestyle). Other students from the Center for Universal Access and Disability Support at the UFS also excelled.

Dineo Mokhosoa (cerebral palsy) won three gold medals (long jump, shot-put, and discus), while the athlete Louzanne Coetzee (blind) shattered the world record in the 5 000 m, as well as the Africa record in the 1 500 m. Juanré Jenkinson (cerebral palsy) won two silver medals (discus and shot-put) while Danie Breitenbach (blind) won two gold medals (800 m and 1500 m).

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