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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS Faculty of Theology hosts expert on African Traditional Religion (ATR)
2016-05-20

Description: African Traditional Religion  Tags: African Traditional Religion

Dr Nokuzola Mndende, Prof Fanie Snyman (Dean of the Faculty of Theology), and Dr Luvuyo Ntombana (Department Head: Religion Studies)

Dr Nokuzola Mndende, an acclaimed theologian, researcher, and practitioner of African Traditional Religion (ATR), is often called upon in the media to offer her expert opinion or participate in interfaith panel discussions. Thanks to an initiative from the postgraduate diploma class in the Faculty of Theology and the efforts of Dr Luvuyo Ntombana (Department Head: Religion Studies; Faculty of Theology), Dr Mndende accepted an invitation to present her paper, “From the periphery to the centre: African Traditional Religion in a democratic state”, on the Bloemfontein Campus of the University of the Free State (UFS). In his opening remarks, Dr Ntombana stated that he was heartened by his students’ desire to be “co-workers in knowledge production” by engaging with Dr Mndende.

Dr Mndende’s contention is that African Traditional Religion (ATR) was suppressed throughout colonial times, and, despite a 22-year-old democracy, continues to be moved to “beyond the periphery” by what she terms “spiritual subsets”; those who strive to amalgamate their African Traditional Religion rituals with the practices of Christianity. Quoting statistics from a 1995 survey by the SABC, she stated that ATR is a minority in its birthplace (with only 5% representation), and posed the question: “If ATR is a minority in its place of birth, where is it a majority?” Her presentation put forward the need to study and interpret ATR introspectively, but acknowledged that more “homework” would be needed in this regard.

Dr Mndende thanked the university, Dr Ntombana, and the Dean of the Faculty of Theology, Prof Fanie Snyman, for inviting her, and expressed a desire for the relationship with the UFS to continue.

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