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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

German Ambassador speaks on universities as agents for transformation
2016-05-25

Description: German Ambassador speaks on universities  Tags: German Ambassador speaks on universities

Eva Ziegert, JC van der Merwe, Lindokuhle Ntuli, Anita Ohl-Meyer, Ambassador Walter Lindner, Tali Nates, and Prof Leon Wessels at the dialogue session hosted by the IRSJ
Photo: Johan Roux

“Change is facilitated through education, not by means of radicalism, violence, or revolution.” Speaking at the Bloemfontein Campus of the University of the Free State (UFS) on Thursday 12 May 2016, the German Ambassador, Walter Lindner, urged students to engage in profitable dialogue instead, keeping their values and ideals in mind while changing the system from the inside.

The Institute for Reconciliation and Social Justice (IRSJ) hosted a full day of dialogues and discussions, the highlight of which was a critical dialogue with Ambassador Lindner, entitled “Universities as agents of transformation in society—Germany’s experience with the student protests of the 1968 movement and the difficulties it has reconciling with its past.” This was followed by a student colloquium, hosted by the Student Representative Council, which concluded with the second in the Africa’s Many Liberations seminar series, co-hosted by the IRSJ and the International Studies Group (ISG), with the title of “Fanon and the relevance of personal and collective decolonisation in today’s South Africa”.

Mr Lindner related his experience of student protests in Germany during the late 1960s, drawing certain parallels with South Africa’s own recent protests. According to Ambassador Lindner, it is “the impatient youth that drives forward change”, but cautioned against radicalism as a long-term solution.

Pointing out the various challenges facing humankind today, such as the lack of natural resources, unbridled climate change, and population growth, Mr Lindner stated that politicians (and the youth of today) would do well to focus on these greater issues, rather than focusing on the more mundane issues with which they are faced on a day-to-day basis.

The subsequent dialogue session was facilitated by Tali Nates, Director of the Johannesburg Holocaust and Genocide Centre. A diverse array of questions and comments, both radical and more conservative, was directed at the ambassador, which he handled with unflappable aplomb.

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