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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
Young dynamic lawyer in the Mail and Guardian Top 200
2016-06-27
Adv Loyiso Makapela
Photo: Stephen Collett
Each year the Mail and Guardian produces a special report on that year’s top 200 young South Africans who inspire, have talent, and drive. This year, we celebrate one of our own, Adv Loyiso Makapela, who has been nominated as one of the top 200 Mail and Guardian Young Achievers of 2016 under the category of Education. Loyiso is an outstanding academic, lecturer and mentor. At age 27, she is the youngest lecturer in the Faculty of Law.
With two Master’s degrees under her belt, she has been awarded the Desmond Tutu Doctoral scholarship by the National Research Foundation and will commence her PhD at both the University of Stellenbosch and Vrije Universiteit in Amsterdam July 2016. With a keen focus on research, she has presented papers and chaired sessions at various conferences locally and internationally in, for example, the United Arab Emirates and Greece, and in Oxford, England.
“The fact that I was nominated under the category ‘Education’ is undoubtedly one of my proudest achievements to date, because there is nothing I am more passionate about and love than the education of young South Africans, particularly women. This is only the beginning, and I hope my story and accomplishments will inspire others to walk out in determined pursuit of their goals and dreams,” said Loyiso.
She is in the final stages of launching a lifestyle website that aims to engage young and ambitious South African women, titled “Young Women of Power”. Through this platform, Loyiso hopes to bring together influential women in business and politics, to empower and enlighten younger women.
The Mail and Guardian Top 200 Young South Africans have, over the years, positioned themselves as leaders in their fields and gained local and international acclaim. The selected 200 will be announced later this month.