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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Race, technology, and maritime labour in the 19th century
2016-06-23


Prof John T. Grider

 

“When employers
impose
worker identity,
it creates problems.”

What does identity mean to people today, and how is it formed? Religion, politics, race, ethnicity, and gender make up individual and community identity. However, Prof John Grider (University of Wisconsin – La Crosse) is of the opinion that employment moulds our identity, since we spend so much time on the job.

Prof Grider joined the Institute for Reconciliation and Social Justice (IRSJ) on the Bloemfontein and Qwaqwa Campuses to discuss his research on the maritime industry, published in his book, Foreign Voyage - Pacific Maritime Labour Identity: 1840 to 1890. “When employers impose worker identity, it creates problems,” he said. Particularly, this “creates instability in communities, and a vulnerability and insecurity amongst the employees”.

To illustrate his point, Prof Grider expanded on the history of 19th-century Atlantic sailors, a highly-skilled workforce, who failed to adapt to changes in their labour environment. Initially, the sea-faring community was very diverse racially. However, as the Pacific, and particularly Asian, marine community gained precedence, this tide turned to such an extent that, in 1886, the Atlantic sailors formed their own Coastal Seamen’s Union in San Francisco, causing a split between Asian and non-Asian sailors. Atlantic sailors had failed to integrate with the new technology of the day (steam power), nor had they accepted the demographic changes that flooded their community rapidly with cheap labour from Chinese shores. 

Prof Grider highlighted the need to maintain an adaptable mentality in the ever- and rapidly-changing labour world, since division amongst workers could lead only to further exploitation of the workforce.

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