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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS acquires Willem Boshoff’s digital archive
2016-07-22

“I do not want to be the only person or artist that is part of this archive, but I want it to expand and involve others too.”

These were the words of Prof Willem Boshoff, the renowned artist and, Associate Professor in the Department of Fine Arts, during the presentation of the Willem Boshoff Archive to the University of the Free State (UFS) Johannes Stegmann Art Gallery during the Vrystaat Arts Festival.

The digital archive may be consulted at the Department of Art History and Image Studies. Large parts of it will also be available on the UFS website at http://scholar.ufs.ac.za.

Conversations surrounding the digital archive

In a discussion led by Dr Francis Halsall from the National College of Art and Design, Dublin, Ireland, the discussion led to the discovery of various themes, including The idea of research, education and dialogue, doing or making, the organisation of knowledge, language and translation, word and figures or people, and the enthusiastic amateur.

Artwork attracts international attention

Alongside Prof Boshoff and Dr Halsall, many other participants who have been inspired by the artist’s work sat in on the discussion about the archive.

They included Ivan Vladislavic, author of Willem Boshoff (2004), Dr Katja Gentric, whose doctoral dissertation at the University of Bourgogne (2013) is on Boshoff’s work, and Helene Smuts, arts education writer and publisher. Josef van Wyk, a Master’s student working on Prof Boshoff’s archive, and Prof Johann Rossouw, Associate Professor of the Department of Philosophy also formed part of the discussion.

Vladislavic mentioned that Prof Boshoff’s work opens up a different form of conceptualisation. “When I first encountered Willem’s work, I was excited by it from an art historic perspective,” he said.

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