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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

The Shepherd Centre celebrates decade of empowering spiritual leaders
2016-08-01

The Shepherd Centre functions under the auspices of the Faculty of Theology at the University of the Free State (UFS), and arose out of a need for non-denominational adult-learning programmes for those actively involved in the ministry. According to the director, Dr Gerhard Botha, the centre came into being to assist spiritual leaders: “The Shepherd Centre takes on the shepherding responsibility for spiritual leaders of all Christian churches.”

Planning started in 2005, when the need was identified for foundation-phase education in the wider church community. Dr Botha was appointed as the director of the centre in 2006, and given the task of compiling a suitable curriculum. The aim of the curriculum is to enable spiritual leaders to provide current interpretations of scripture for a modern society. From the first handful of students a decade ago, The Shepherd Centre has grown by mid-2016 to 300 adult learners enrolled in the short learning programmes, many of which are catered for at the satellite sites in Kimberley, Koffiefontein, Kroonstad, Qwaqwa/Kestell, Thaba Nchu, Zeerust, and the South Campus of the UFS.

This initiative has extended its reach even further than the boundaries of the Free State. In 2014, Dr Botha and Prof Fanie Snyman, Dean of the Faculty of Theology, visited Ethiopia, and signed an agreement of mutual collaboration with the Full Gospel Church there. In addition, a Shepherds4Africa programme is involved in Christian communities and with Christian religious leaders in several other countries, providing training opportunities to various indigenous churches, with the greater vision of spreading the Word to all countries in Africa and beyond. Dr Botha states that their hope is to provide the tools needed in order to make the community of faith as healthy so as to build its moral fibre.

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