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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Offender learners get unique opportunity
2016-08-02

Description: Mandela Day Project  Tags: Mandela Day Project

Subashini Moodley, Regional Commissioner Northern Cape
and Free State.
Photo: Rulanzen Martin

Nelson Mandela spoke of education as the tool of liberation. Kamogelo Dithebe, Chairperson of the Postgraduate Student Council (PGSC), opened the PGSC’s Mandela Day Project with these striking words.

The PGSC at the University of the Free State (UFS) hosted the Tswelopele Correctional Service Centre Career Day for their annual Mandela Day project on the Bloemfontein Campus on 27 July 2016. Grade 11 and 12 learner offenders from the Kimberley-based centre were given a tour of the campus.

Visitors empowered with knowledge

Subashini Moodley, Free State and Northern Cape Regional Commissioner, said: “It is really a privilege to be here today. It is not every day you see a Correctional Centre roaming around campus.” She thanked the postgraduate council for making the opportunity possible, as it was the first open day for the offender-learners in collaboration with the PGSC.

She told the offender-learners that they were privileged to be given the opportunity as many learners in a normal school environment often come to university not knowing what to expect or what to study. She said they should empower themselves with knowledge as they met with the different faculties.

Tour encourages and change lives

Mthulisi Zandile, a Grade 12 offender learner, was very excited to learn about the career options available after completing a university degree. “It means a lot to us as it will further our education, and bring change in our life, as this will show me the right route to pass matric with flying colours,” said Mthulisi.

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