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07 January 2018
Photo Charl Devenish
Dr Anneke van der Spoel van Dijk is invested in contributing
to the global effort of stopping TB by 2035.
The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB).
She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB).
Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.
Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”
Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”
As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.
New online journal repository launched during research week
2016-08-03
Open Access core team.The annual research week marked the official launch of KovsieJournals published on KovsieScholar, the UFS output repository. Library and information Services and the office of the Vice Rector: Research, Prof Corli Witthuhn, hosted the week-long events of 26-29 July 2016 on the Bloemfontein Campus.
KovsieScholar is the UFS’s research repository that collects, preserves, and distributes open access digital material. It is an important tool for preserving the university’s legacy, facilitating digital preservation and scholarly communication. It aims to increase the university’s global visibility, the impact and profiles of its researchers, and contribute to the preservation and sharing of knowledge. Currently, it holds journals published since 2010.
The main launch event of 27 July was opened at the Equitas Building’s Senate Hall by Mr Charlie Molepo, Deputy-Director: LIS Research and Scholarly Communications, who also presented the project background. Prof Jonathan Jansen, Vice-Chancellor and Rector said it is a great initiative that will allow anyone to have access to UFS research outputs anywhere in the world, something he is glad to see happening during his term.
A roundtable discussion brought together more than ten senior professors and heads of department to explore topics such as Open Access and its benefits and pitfalls, centralisation of institutional research output, and the future publishing platform of KovsieJournals, amongst others. Research Week will end with training for Open Access and Centre for Teaching and Learning’s core teams.