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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Meet our Council: Likeleli Mphutlane
2016-08-03

Description: Likeleli Mphutlane  Tags: Likeleli Mphutlane

Likeleli Mphutlane

The University of the Free State (UFS) has long been considered a leader in diversity.  Its diverse character is nowhere more apparent than on the UFS Council, where different voices with differing viewpoints and diverse cultural backgrounds strive to lead the institution to greater heights.

One such voice belongs to Likeleli Mphutlane, who has been serving on the UFS Council since 2015. This dynamic young woman was born in Bethlehem, raised in Lesotho, and matriculated at Louw Wepener High School as a Matriculant of the Year Top 14 finalist.

Studies at the UFS


She completed a BAcc degree at the UFS, while serving as vice-primaria of Welwitschia Residence, after which she obtained a BAcc Honours degree from the University of South Africa.

She qualified as a Chartered Accountant in 2014. After gaining work experience at PricewaterhouseCoopers and SAB, she works now as an independent consultant in her own company, Inspire Innovation Business Consultants.

Likeleli serves on the audit and risk committee and the financial committee of the Council.

The difference she makes

"I believe that my role on the Council is to share my expertise and skills to ensure that the university upholds the highest standards of governance, and achieves its objectives of remaining financially sustainable. I also think that, as a black female alumnus, I bring a diverse viewpoint to the Council," she says.

While her responsibilities as co-founder of the Lesotho Young Professionals Forum, and chairperson of the Free State branch of the Association for the Advancement of Black Accountants South Africa, keep her busy, she enjoys physical activity, and travelling with her husband, Stephen Monyamane.

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