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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Africa’s lost voice during the Second World War echoes throughout book
2016-08-24

Description: Second World War book launch Tags: Second World War book launch

Prof Judith Byfield and Prof Heidi Hudson at the
book launch of Africa and Second World War at the
UFS Sasol Library.
Photo: Rulanzen Martin

If you pick up any historical record on the Second World War, you would see that, to a large extent, Africa has been missing from the history pages until now.

Africa and the Second World War (WW II) is a book edited by Prof Carolyn Brown from Rutgers University and Prof Judith Byfield from Cornell University in the United States. The book is the outcome of various papers presented during a workshop at Rutgers University and at a conference on WWII hosted at Cornell University.

The co-editors of the book were invited by Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), to launch the book at the UFS. The Centre for Africa Studies at the university, in collaboration with the UFS Sasol Library, presented the launch on Tuesday 16 August 2016.

Bestowing honour upon Africa’s role during WW II
Many people do not know that WW II started in Ethiopia with the Italian Invasion. This is generally omitted from discussions or complete histories of WW II. The present book explores the experiences of male and female combatants, peasant producers, women traders, missionaries, and sex workers during the war. “Many people are not aware that Africa produced most of the mineral and agricultural during the war,” said Prof Brown.

Book to reach a greater audience for discussion
The co-editors hope that the book reaches people who teach WW II history, as many talk about only the nationalist movements. “The opening of the book also talks about the importance of South Africa during WW II,” said Prof Byfield. The authors hope that people will read the book to start thinking comparatively about the war.

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