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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Incidents on the Bloemfontein Campus
2016-08-25

Statement by the Institutional Forum of the University of the Free State (UFS) - Released by Dr Willy Nel (Chairperson) on behalf of the Institutional Forum of the UFS

 

Two incidents happened on campus the past week, which were brought to the attention of the university management:

1. The university management received a complaint on 16 August 2016 that a student had sprayed liquid in the face of a security guard at one of the university gates. The reason appears to be that three students were sent back to their residence to collect their student cards in order to exit the campus – as required – and this might have caused the reaction. In video footage, it is clear that a student on the passenger side was responsible for the spraying incident. Statements have been taken from the three students in the car as well as from the affected security guard. The student claims that the liquid was water from his gym bottle. Regardless, charge sheets were prepared and delivered, and the disciplinary hearing has been scheduled on an urgent basis for 1 September 2016.

2. An incident happened on the Bloemfontein Campus on 23 August 2016, with a test being distributed in a class where the answer to one of the questions was included in the Afrikaans version, while it was excluded in the English version. The matter was investigated and it was decided that the written test will be set aside and a new test, covering the same scope, will be compiled for all students; the new test will be subject to external moderation; and external moderation of tests in the particular department will take place until the end of the year. The lecturer concerned claims that this was a genuine mistake and not intentional, in that guidelines for that one question were removed after a decision to add further examination questions, which made the guidelines obsolete; in the process of revising the papers, the lecturer made a mistake and did not remove the guidelines for both the English and Afrikaans versions. Nonetheless, the university management has decided on a disciplinary process involving the lecturer concerned, given the seriousness of the matter.


Released by: Lacea Loader (Director: Communication and Brand Management)
Tel: +27 51 401 3422/2707 or +27 83 645 2454
Email: news@ufs.ac.za  | loaderl@ufs.ac.za
Fax: +27 51 444 6393


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