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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

‘Captivating, powerful’ exhibition debuts at UFS
2016-08-29

Description: Sue Williamson exibition Tags: Sue Williamson exibition

Sue Williamson, What is this thing called freedom?, 2016 (two-channel video, 19min 25s)

A new exhibition by internationally-recognised artist, Sue Williamson, entitled No More Fairytales, was launched in the Johannes Stegmann Gallery on the Bloemfontein Campus of the University of the Free State (UFS) on 18 August 2016. The exhibition takes the audience on an exploration into the long-term effects of South Africa’s violent past.

No More Fairytales features two new video works. In It’s a pleasure to meet you, Candice Mama and Siyah Mgoduka—whose fathers were killed by Eugene de Kock—talk about living with loss, holding, on, and letting go. The other video, What is this thing called freedom?, draws the audience into a conversation between three generations of women in the Siwani family, who talk about the humiliations of apartheid, student unrest in the 1980s, and the recent #FeesMustFall protests.

“It’s all about opening up conversations.”

Both of these works have already been invited to participate in international exhibitions, the first of which, Un Autre Continent, opens in Le Havre, France, in September 2016. The videos will appear in 2017 in Without Drums and Trumpets—100 Years of War, also in France. The exhibition will run until 16 September 2016 at the UFS.

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Sue Williamson, It's a pleasure to meet you, 2016 (two-channel video, 25min)

“There is such an energy to this large piece of work; there is something captivating, something powerful about its vibrancy,” said Prof Pumla Gobodo-Madikizela, Senior Research Professor in Trauma, Forgiveness and Reconciliation Studies at the UFS. The series was commissioned by Prof Gobodo-Madikizela as part of the project, ‘Trauma, Memory and Representations of the Past: Transforming Scholarship in the Humanities and the Arts’. The five-year research project is funded by the Andrew W. Mellon Foundation through a grant of R10 million.

The launch of the exhibition was followed the next morning by an insightful dialogue session between Prof Gobodo-Madikizela, Mama, Mgoduka, Williamson, and the audience. “It’s all about opening up conversations and trying to bring out things that have been so painful and so hurtful in this country,” Williamson said.

 

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