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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS Qwaqwa Campus cross-country team qualifies for national championships
2016-08-30

Description: Qwaqwa Campus cross-country team  Tags: Qwaqwa Campus cross-country team

UFS Qwaqwa Campus’ cross-country team that has
qualified for the SA Championships in the
Western Cape. They are, from the left: Malema Hlubi,
Lesedi Radebe, Moorosi Semase, and their coach,
Boy Soke.

The University of the Free State Qwaqwa Campus’ cross country team has had a successful season so far. The team has competed in the Eastern Free State Championships that were recently held in Bethlehem, where they qualified to compete provincially in Bloemfontein and eventually, nationally in the Western Cape.

During the Bethlehem meeting, rising star Moorosi Semase clocked 27:26 in the under-19 8-km category, whilst in the 4-km under-22 section Kovsie team mates reigned with ease as they occupied all four top positions. Malema Hlubi was the fastest in 11:13, followed by Lebohang Miya (11:33), Lindokuhle Miya (11:39), and Lebohang Tsotetsi (11:45). In the senior 10-km race, Lesedi Radebe and Bheki Sishi respectively came first and second. These results qualified them for the Free State Championships that were held in Bloemfontein on 13 August 2016.

In congratulating his charges, their coach and astute runner himself, Boy Soke said: “I am very proud of the achievements of these dedicated athletes. It is through their dedication and hard work that we have qualified for the National Championships in George in the Western Cape on 10 September 2016.”

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