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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Heritage translates into fashion
2016-09-13

Description: Centre for Africa Studies Tags: Centre for Africa Studies

Vuyo Mbutho, winner of the best dressed
traditional wear, and Palesa Mokubung,
acclaimed fashion designer.
Photo: Siobhan Canavan

There is no such thing as overnight success. You need to earn your way to the top through hard work, which is exactly what critically acclaimed fashion designer Palesa Mokubung did.

During the 2016 Heritage Day lecture hosted by the Centre for Africa Studies, entrepreneur, award winner and fashion visionary Mokubung told how she had begun her career with the label Stoned Cherrie. Kroonstad-born Mokubung then formed her own label in 2004 called Mantsho, which is Sesotho for “brutally black”.

A true Mantsho garment can be identified by three elements that describe Mokubung’s knowledge of her craft, namely its confident and effortless silhouette, structure and quirkiness. “I was taught to express myself from a very young age and my job is to give people life through my clothes,” she says.

Under the management and creative leadership of Mokubung, Mantsho has gone on to travel to places such as Greece, India, New York, Jamaica, Nigeria, Botswana, and Senegal showcasing its designs.

Mokubung says she does not look far for inspiration because she lives in such exciting times. “Sometimes the fabrics talk to you and you should listen to them.”

This confident, straight talker with her high standards says that all aspiring fashion designers need to earn their way to the top. “You get over it by getting over it, and by working through it.”

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