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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Growth in scholarly books ‘is remarkable’
2016-09-16

Description: Scholarly Books 2016 Tags: Scholarly Books 2016

The UFS is proud of the variety of books and
scholarly articles published by scholars
in various fields.
Photo: Charl Devenish

The UFS has shown steady growth in its output of scholarly articles. Dr Glen Taylor, Senior Director of Research Development, says “the UFS has shown remarkable growth in the output of scholarly book publications over the recent years." The 13,83 subsidy units from scholarly books in 2010 has grown to 98,52 in 2014, elevating the university to fourth position nationwide. 

“It is encouraging for the research office to see that the number of books has increased over the years, together with the units we receive for subsidy, but also the steady increase in the quality of our scholarly books in general,” he said.

Contributors to the growth in scholarly publications include Dr Christian Williams of the Department of Anthropology, celebrated journalist Zubeida Jaffer, as well as JC van der Merwe, the Deputy Director of the Institute for Reconciliation and Social Justice (IRSJ), and Dionne van Reenen, researcher and PhD candidate at the IRSJ. Dr Williams received the 2016 Distinguished Scholar Book Prize at the official opening of the UFS earlier this year. The book, National Liberation in Postcolonial Southern Africa: A Historical Ethnography of SWAPO’s exile camps, is the first full-length scholarly monograph on SWAPO and Namibians in exile. 
 
The 13,83 subsidy units from scholarly books in 2010 was approximately a 10% increase in outputs from 2005 to 2010. In 2010, the higher education institution sector as a whole produced 401,68 units from scholarly books. The UFS contribution of approximately 3,44% put the university in tenth position. 

“The increase in subsidy for scholarly books should stimulate the sector further, and an increase in scholarly books is expected, which complements the university research output strategy to become a leading research-intensive institution,” Dr Taylor said.

 

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