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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

University of Leeds professor an inspiration
2016-09-19

Description: Academic Conversation  Tags: Academic Conversation

Prof Shirley Anne Tate, Associate Professor
at the University of Leeds; Eddie de Wet and
Emme-Lancia Faro, both from Student
Communities; Pura Mgolombane, Dean of
Student Affairs; and Dr WP Wahl, Assistant
Director of Student Communities.
Photo: Qhamani Tshazi

Prof Shirley Anne Tate from the University of Leeds in the United Kingdom inspired students at the second Academic Conversation held at the University of the Free State on the Bloemfontein Campus.

“Academics such as Prof Tate play a vital role in building bridges between students with high demands of ‘transformation’ and university managements that struggle to meet students halfway.”

These were the words of Jani Swart, current Primaria of Welwitschia residence, who attended the dialogue session. She said, however, she wished that more students had the opportunity and willingness to be guided by Prof Tate.

Prof Tate is an Associate Professor in Race and Culture at the Centre for Ethnicity and Racism Studies, School of Sociology and Social Policy at the University of Leeds. She is also a visiting Professor and Research Fellow at the Institute for Reconciliation and Social Justice at UFS.

Professor Tate captivated the students when she addressed them on the topic of Wellbeing in Higher Education Institutions.

The Academic Conversation was hosted by the Office of Student Affairs on 1 August 2016.

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