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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Prof Solomon appointed to board of flagship journal of UNECA
2016-10-06

Description: Prof Hussein Solomon UNECA Tags: Prof Hussein Solomon UNECA

Prof Hussein Solomon, member of the Editorial
Board of the Afro-Arab Social and Economic
Review. He is also the author of Islamic State
and the Coming Global Confrontation.
Photo: Charl Devenish

“I cannot say I worked towards it – I just did my work, and I guess someone noticed.” These are the words of Prof Hussein Solomon from the Department of Political Studies and Governance at the University of the Free State (UFS), who was recently appointed to the Editorial Board of the Afro-Arab Social and Economic Review.

On an editorial board with people he quoted
This is the flagship journal of the United Nations Economic Commission for Africa (UNECA). The mandate of the Economic Commission for Africa (ECA) is to promote the economic and social development of the states which are regarded as members of the United Nations (UN). Prof Solomon says the board consists of people that he used to quote when he was a student, and to serve alongside them is a privilege.

Book launched in Greece, Japan, and Indonesia

His book, Islamic State and the Coming Global Confrontation, was earlier published by Palgrave Macmillan in London and launched in Greece, Japan, and Indonesia in June and July 2016 respectively. It analyses the origins and organisational structure of the Islamic State (IS), ans examines its military triumphs and success in securing new recruits via social media.

Exploit of IS vulnerabilities to combat organisation
Prof Solomon says the IS makes use of the winning hearts and mind (WHAM) principle where they earn the trust of residents by providing basic services, and the only solution we have is to “exploit the Islamic State’s vulnerabilities and to highlight their atrocities.”

He mentions that a lot needs to be done to overcome the IS. It is vital to have boots on the ground and an acceptance that countries will splinter. An overarching strategy needs to be in place which allows for regional variations, good governance, and the countering of extremism.

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