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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Community builders honoured at Community Engagement Awards
2016-10-13

Description: "06 -10-2016 Comm Engagement Awards Read More Tags: Comm Engagement Awards

Photo: Charl Devenish

The office of Community Engagement held its annual Community Engagement Awards at the University of the Free State (UFS) on 5 October 2016. This year, the ceremony celebrated people who gave themselves selflessly to improve the lives of those around them who are less privileged. Key players in various sectors of society were recognised and honoured for their contribution and commitment towards a common good.

Dr Richard Teare, president of the Global University for Lifelong Learning (GULL), was the keynote speaker at the ceremony. GULL, a non-profit foundation, operates across the world, providing access to lifelong learning for communities, giving each individual an opportunity to make a difference in their world. Dr Teare talked of places that lack the provision and infrastructure to access higher education and said that through community service programmes, social and economic development was enhanced, and the necessary expertise and resources were provided to drive a community towards a greater good. “Community engagement espouses academic excellence—it enables people to discover their full potential.”

Through its partnership with GULL, the University of Free State has worked with women from Bloem Shelter, an organisation that provides assistance to underprivileged women and children from diverse walks of life. The women were equipped with the necessary skills and knowledge they needed to become self-sufficient - an experience that has yielded positive, constructive change in the women’s lives. 

The awards also acknowledged the boldness and innovative support of members of the Free State community in their various sectors. Among those awarded was Dr Choice Makhetha for her contribution in building capacity for those involved in community service programmes. She also designed and created approaches to improve situations in schools, churches, community organisations and small businesses. Also presented with an award was Dr Dipane Hlalele of the Qwaqwa Campus for his role as principal investigator in two National Research Foundation (NRF) -funded projects; Rural Relational Leadership and Sustainable Rural and Urban Connection. The ICT Innovation in School Education division of the South Campus was also recognised for its Internet Broadcast Project (IBP), which provides lessons on different subjects to 72 000 learners and 3 000 teachers each week.

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