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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Postgraduate studies can open doors to a successful career – Top 50 Economics students advised
2016-10-18

Description: Top 50 Economics students  Tags: Top 50 Economics students

Economics 4: Students Veda Hendrikse and Merrylyn Shumba, Chris Scheepers (Sanlam), Dr Johan Coetzee and Johannes de Klerk (Sanlam).
Photo: Leatitia Pienaar

The Department of Economics in the Faculty of Economic and Management Sciences held a reception for its top 50 students on 10 October 2016 on the Bloemfontein Campus.

Speaking at the event, Mr Rocco Carr, business development manager at Glacier Investments by Sanlam, encouraged students to enrol for postgraduate studies in Economics and Financial Economics. He said the South African economy was not stable at the moment due to various factors such as politics. However, it was interwoven with the global economy and circumstances might change to make the country prosperous again in the future. ”The interest rates, the upcoming presidential election in the US, the economic changes in China, Brexit, and the economic changes in the European Union are some of the factors that are at play in the South African economy,” he said.

He further encouraged students to be prepared for the workplace by developing their work ethic and learning to take responsibility as this would help them grow a successful career despite economic volatility.

Dr Johan Coetzee, acting head of the Department of Economics, said the three honours programmes – Economics, Financial Economics and Investment Management, and Applied Econometrics – were internationally accredited and could open many doors to students. “Training is not only about what you can do, also how you think and how you manage people. Managing people has become more important than ever before,” Coetzee said.

The department hosts its top 50 students each year to expose them to courses they can take at postgraduate level and the career opportunities that lie ahead.


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