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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

International success for UFS Professor in Japan
2016-12-07

Description: Professor Solomon in Japan  Tags: Professor Solomon in Japan  

Prof Hussein Solomon from the UFS was recently
appointed as Visiting Professor at Osaka University
in Japan.
Photo: Charl Devenish

He has been involved with the Osaka University for several years, but Prof Hussein Solomon’s recent appointment as Visiting Professor will allow the University of the Free State (UFS) and Osaka to work on long-term issues.

Kovsie academics hold their own internationally

His appointment at the university in Japan came as no surprise as he is a regular teacher to students and leader of seminars to staff. According to Prof Solomon, Senior Professor at the Department of Political Studies and Governance at the UFS, Kovsie academics can hold their own internationally.

The Faculty of Humanities has a memorandum of understanding with Osaka School of International Public Policy (OSIPP), which consists of Political Science, Public Administration, Law and Economics at Osaka University.

Enhancing the universities’ relationship

“I have been involved with Osaka since 2007, initially with their Global Collaboration Center (GLOCOL), focusing on conflict resolution, and then later with OSIPP.”

Although Prof Solomon has been working with Osaka for a while, his appointment will enhance the relationship between the universities.

“We have been cooperating with Osaka for some time, hosting annual conferences, engaging in staff and student exchanges, as well as the establishment of the international centre. This appointment allows us to work on longer-term issues allowing us to chase funding together and deepen our existing linkages,” he says.

UFS doctoral students being jointly supervised

Prof Solomon says that he would like to see the doctoral students from the UFS being jointly supervised. “We already have one of our doctorial students, Alta Vermeulen, who is being co-supervised between myself and Prof Virgil Hawkins from Osaka,” he says.

Prof Solomon was also recently appointed to the board of flagship journal, United Nations Economic Commission for Africa (UNECA).

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