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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Second OSM concert inspires Heidedal youth
2016-12-08

Description: OSM Heidedal concert Tags: OSM Heidedal concert 

Sehle Mosole, left, and Jonandrea Pofadder back,
with the children from the ROC Foundation during the
second OSM community outreach in Heidedal, Bloemfontein.
Photo: Supplied

“The project is special because it is an event in the community, by the community.” This is what Gerda Pretorius, lecturer in the Odeion School of Music (OSM) at the University of the Fee State, said about the second music concert hosted by the OSM in Heidedal, Bloemfontein.

The concert, in collaboration with the Reach Our Community (ROC) Foundation on 26 November 2016, was a follow-up on the concept that was started last year. As part of the outcomes of the MUSE3706 module, the third-year Music Education students engage in a project in a specific environment.  For this project the MUSE team, led by Pretorius and Anchen Froneman, collaborated with the ROC Foundation in Heidedal. Two third-year students in the OSM, Sehle Mosole and Jonandrea Pofadder, facilitated the event in 2016.

Long relationship between ROC and UFS

Since 2008, the UFS has successfully partnered with ROC through service-learning and community-engagement projects in which students from across all seven faculties participate. The foundation strives to address the challenges resulting from factors such as poverty, unemployment, HIV/Aids, single parenting, lack of guardianship, and physical and sexual abuse. In the Afterschool Care programme, the children engage in educational, cultural, and recreational activities.

Children who form part of the foundation’s Afterschool Care programme, showed their impressive music skills to their parents and guardians in attendance.

Spontaneous participation by community

“I was deeply touched by the spontaneous participation and appreciation of the community for art-related – in particular music and dance – events,” said Pretorius. A highlight was the community’s involvement in the event and the value it adds to the students’ organising skills.

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