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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS Faculty of Health Sciences celebrates its newly qualified doctors
2016-12-09

Description: MBChB final-year students  Tags: MBChB final-year students  

The UFS medical students who obtained their
qualifications Cum Laude are: front row: Dr Madeli Jonker,
Dr Corli Leonard, Dr Jacques Kok, Dr Kelly Fuller.
Back row: Dr Henco Nel, Dr Dan Holmberg,
Dr Rikus Hoogenboezem and Dr Ben van Niekerk.
Photo: Marie-Louise du Toit


“Kovsies’ doctors stand out. They go the extra mile. Go out there and be a true representative of Kovsies’ servanthood.” These were the words of Prof Gert van Zyl, Dean of the Faculty of Health Sciences, at the annual function that was held by the School of Medicine for final-year medical students.

The function celebrates students who have obtained their MB ChB degrees, becoming qualified doctors. Prof Van Zyl went on to congratulate the students for thriving in a difficult year.  “From today onwards, your degrees are in the bag, and nobody can take that away from you,” said Prof Van Zyl.

Class of 2016 praised for their tenacity

A total of 116 students obtained the qualifications, and were acknowledged as the class that showed the most tenacity, commitment and dedication to their studies. Nine students obtained their MB ChB qualifications Cum Laude. The medical students will be graduating at the UFS Summer Graduations on 8 December 2016.

Henco Nel, Michael Linström, and Daniel Holmberg were recognised as the best overall performing students in the class of 2016. Nel received prizes for best student in the departments of Urology and Orthopaedic Surgery; Linström walked away with awards from the departments of Anaesthesiology, Family Medicine and Obstetrics and Gynaecology, and Holmberg in Internal Medicine, and Paediatrics and Child Health.

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