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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

2016: The year that was on the Qwaqwa Campus
2016-12-19

Description: Dr Lehlohonolo Koao, Qwaqwa highlights 2017 Tags: Dr Lehlohonolo Koao  

Dr Lehlohonolo Koao believes his research
will improve ordinary lives.
Photo: Thabo Kessah

Description: Prof Lis Lange, Qwaqwa highlights 2017 Tags: Prof Lis Lange, Qwaqwa highlights 2017

Prof Lis Lange making a point about
the governance, leadership, and
management processes at the university.
Photo: Thabo Kessah

Description: I-DENT-I-TIES, Qwaqwa Campus highlights 2017 Tags: I-DENT-I-TIES, Qwaqwa Campus highlights 2017

One of the leading performers of
I-DENT-I-TIES, Baanetse Mokhotla.
Photo: Thabo Kessah

The year 2016 has seen the Qwaqwa Campus become a hive of activity from all fronts.

Lithium-ion batteries research

On the research front, Dr Lehlohonolo Koao started work on the research that is aimed at improving lives of ordinary people. His research project focuses on improving the efficiency of lithium-ion batteries that are now commonly used in portable electronics, such as cellphones and laptops.

“This study will enhance power retention in the batteries for improved daily life since cellphones, solar panels, and laptops, to mention only a few, are now a way of life.’’

Dr Koao is a Senior Lecturer in the Department of Physics, where he specialises in solid state materials. He is also a member of the Vice-Chancellor’s Prestige Scholars Programme.

Spotlight on the academic project

To create a conducive teaching and learning environment on the campus amid the academic difficulties experienced during the year, the Institute for Reconciliation and Social Justice (IRSJ) hosted a critical conversation that was facilitated by Vice-Rector: Academic, Prof Lis Lange.

Prof Lange interacted with students who asked her very difficult, but critical questions relating to internal UFS processes aimed at academic excellence. Issues that were discussed included developing a common understanding on governance, leadership, and management processes at the university.

Student talent unearthed

This was a year during which massive student talent was unearthed by an unusual stage play called I-DENT-I-TIES. This large-scale interdisciplinary performance project afforded Qwaqwa students an unforgettable experience. This was according to Baanetse Mokhotla, one of the leading performers.

“I have personally learnt a lot about performing arts and also grew as an individual.”

The creative minds behind the play included New York-based Dutch director, Erwin Maas; Vienna-based Dutch theatre designer, Nico de Rooij; Djana Covic, a Serbian performance-craft-artist based in Vienna; and South African film and stage legend Jerry Mofokeng. The production was part of this year’s Vrystaat Arts Festival in Bloemfontein.

 

 

 

 

 

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