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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS PhD scholar honoured by Free State MEC of Education
2016-12-12

Description: Thabo Sithole  Tags: Thabo Sithole  

Thabo Sithole was awarded a National Teaching Award
for excellence in teaching Physical Sciences.
Photo: Aneka van der Merwe

Thabo Sithole, a PhD student at the University of the Free State’s (UFS) Faculty of Education, was recently awarded a prestigious award during the provincial National Teaching Awards in November at which he was celebrated along with other teachers from the Free State.

Sithole was awarded for excellence in teaching Physical Sciences, using a variety of strategies to appeal to the different abilities of learners.

He holds a BSc Medical Microbiology, BSc Chemistry, BCom Economics, BSc Hons in Chemistry, BCom Hons in Economics and MA in Mathematics. To qualify to become an educator, he completed his Postgraduate Certificate in Education (PGCE) at UFS.

Apart from teaching, Sithole assists youths confronted with substance abuse and was instrumental in getting funding to assist young people in Jacobsdal. The Albertina Sisulu Youth Recreation Centre in the town now receives annual funding from the Free State Department of Social Development.

Through the National Teaching Awards, the Department of Basic Education acknowledges the extraordinary efforts of teachers, often achieved under very difficult conditions and in service to children from underprivileged families and economically depressed communities.

Leadership is a crucial element to all schools functioning at optimum with all teachers, learners and parents moving forward with a common vision for the improvement of the school.

Sithole’s work also focuses on clustering childhood development centres to work together in order to enhance the preparedness of learners entering primary school. The MEC for Education, Mr Tate Makgoe, said the National Teaching Awards recognised and promoted excellence in teaching.

The UFS Faculty of Education congratulated all teachers in South Africa who worked tirelessly to build a better future for all learners.

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