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Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

UFS main campus and Vista campus students’ simultaneous graduation a first
2004-12-01

Altogether 284 students from the University of the Free State’s (UFS) main campus and the Vista campus will for the first time graduate during the same ceremony on Thursday 2 December 2004, following the incorporation of the Vista campus into the UFS in January this year.

The ceremony will mainly comprise of the graduation of students from the UFS’s Faculty of Health Sciences. Students from the Vista campus who will be graduating include those from the Faculties of Economic and Management Sciences, Humanities, Law and School of Education. One doctorate will be awarded to a student from Vista campus’ School of Education.

During the ceremony, the first group of students who completed the five-year programme for the MB ChB-course will be receiving their degrees. The last group of students who completed the six-year programme of the same course will also be receiving their degrees. The six-year programme of the MB ChB-course will be fully converted into a five-year programme as from next year.

Prof Stewart Petersen, from the University of Leicester in the United Kingdom, will receive a shield of honour from the UFS’s School of Medicine for his outstanding contribution to, and input in the medical curriculum 2000 that is used for the training of medical students in this school. Prof Petersen’s advice, ideas and recommendations have helped the School of Medicine to put together a medical programme that is currently considered one of the most innovative teaching and training programmes for medical students in South Africa. He is also involved in the Health Professions Education Programme where he acts as co-supervisor for Ph D students at the School of Medicine.

The ceremony will take place at 14:30 in the Callie Human Centre on the UFS main campus.

Media release
Issued by: Lacea Loader
Media Representative
Tel: (051) 401-2584
Cell: 083 645 2454
E-mail: loaderl.stg@mail.uovs.ac.za
1 December 2004

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