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07 January 2018 Photo Charl Devenish
Researcher tackling drug-resistant TB through molecular methods
Dr Anneke van der Spoel van Dijk is invested in contributing to the global effort of stopping TB by 2035.

The work of Dr Anneke van der Spoel van Dijk investigates the spread of TB in the Free State population using techniques such as next generation sequencing, spoligotyping and MIRU-VNTR typing. Dr Van der Spoel van Dijk, a senior medical scientist in the Department of Medical Microbiology at the University of the Free State (UFS) also looks at drug resistance in her research. This work informs decisions about how best to treat patients with multidrug-resistant TB (MDR-TB). 

She employs rapid molecular techniques to track one of Africa’s most serious diseases, tuberculosis (TB). 

Drug resistance
Scientists assist the National Health Laboratory Service and Department of Health in trying to refine the diagnostic tools to identify these cases earlier. Dr Van der Spoel van Dijk explains: “Until recently, it took up to two years to fine-tune treatment decisions for patients with MDR-TB. Patients get a cocktail of anti-TB drugs, but it takes time to find the right combination. Re-infection and relapse (patients stopping treatment for several reasons) add to the diagnostic and treatment management challenges.

Enormous impact
“Now doctors can reduce the time needed for diagnostic certainty to about seven days, while new drugs allow reduction of treatment from more than 18 to nine months. This can have an enormous impact on the life of many patients.”

Dr Van der Spoel van Dijk’s work forms part of research in the faculty looking at resistance development in TB strains. She is currently also doing her doctoral thesis on the differences and incidence of MDR-TB among adolescents versus adults. Dr Van der Spoel van Dijk says: “It is a complicated picture, but we hope to unravel it to support better diagnostic tools and patient care.”

As part of the National Health Laboratory Service, her department is playing an important role in TB diagnostics and the training of scientists and future pathologists. “Our work is contributing to the global vision to stop TB by 2035,” Dr Van der Spoel van Dijk says.

News Archive

Meet our Council: A teacher with a passion for changing lives
2016-12-19

Description: Henry Madlala, Council member Tags: Henry Madlala, Council member 

Henry Dumisani Madlala

William Arthur Ward once said: “The mediocre teacher tells. The good teacher explains. The superior teacher demonstrates. The great teacher inspires.”

However, a teacher can only be great and inspire when teaching is a passion and a calling.

This is exactly the case with Henry Dumisani Madlala, Councillor of the University of the Free State. Mr Madlala is the principal of New Horizon College, a private school in Harrismith.

High educational standards and quality teaching
“New Horizon College is an independent, non-racial educational institution striving to maintain high educational standards and making quality education accessible to all. We have attained a 100% matric pass rate each year in the past six years since I became headmaster."

"My recipe is simple: teachers must teach and learners must learn.”

Mr Madlala was born and bred in KwaZulu-Natal and matriculated from Amazulu High School. Afterwards, he completed a BSc degree in Mathematics and Physics at the University of the North’s Qwaqwa Campus.

Delegate, govern, and trust
He says: “There are three key management principles which I follow as principal: delegate, govern, and trust. I give responsibilities to people, I make sure that they know what is expected of them, and in the end I trust them to carry out their responsibilities.”

His career as teacher and principal has been full of highlights on which he looks back with satisfaction.

Proud to plough back into the university
Madlala has been serving on the UFS Council since 2010 and has been part of Kovsie Alumni’s executive management since 2011. He is proud to plough back into the university in this manner.

“To me, being a Kovsie alumnus means pride, respect, discipline, and loyalty. Once a Kovsie, always a Kovsie!”

For this reason, Madlala believes that the UFS will play a major role in the country and in higher education for a long time to come.

“The UFS has been in existence for more than a hundred years and will no doubt survive for another hundred years or longer. We are indeed one of the leading universities in the country when it comes to transformation and academic excellence. The survival of the UFS is not a dream, but a reality.”

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